Breast cancer And Abortion

Do u know that when a natural process like pregnancy is terminated,some cells which are undergoing changes ,example:breast cells are left to wander in the body system. these cells may later in a womans life become cancerous.
However, women who have had abortions stand the HIGH risk of developing breast cancer later in their life time.
It may interest u to know that this piece of information may not easily be published because our generation is more interestd in matching the available resources with a certain targeted population.
Hospitals may not tell u the risk of it all.Its all about their Benjamins.
BE WARNED
UZZY

WHATS YOUR SOURCE

i will like u to use any search engine of your choice in the internet to source for this very vital info. or see a doctor who can swallow his/her pride 4 d truth.
Uzzy

uzzy

Please be sure of the info u give. Anyway i will still make a research on it and i will get back to u

Hi!

Please take time to read the attachement.

What is Breast Cancer?

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Breast Cancer Prevention Institute

FACT SHEET…The Biologic Cause of the Abortion Breast Cancer Link: The Physiology of the Breast
May, 2003

The physiology of the breast provides the strongest evidence of the causal link between abortion and breast cancer. The same biology that accounts for 90% of all risk factors for breast cancer accounts for the ABC link.
Simply stated, the biology rests on two principles.

1. The more estrogen a woman is exposed to in her lifetime, the higher her risk for breast cancer. It is well established that estrogen is implicated in the formation of three cancers: uterine, germ cell and breast.1 Estrogen can induce cancers to form in two ways, as a genotoxin and a mitogen. A genotoxin or mutagen directly damages the DNA (causes mutations), initiating a process that leads to the formation of cancer cells. Certain natural metabolites of estrogen have been shown to cause mutations.2 A mitogen causes cells to proliferate, that is, to multiply through division (mitosis). Each a time a cell divides to form two cells, it must replicate its DNA. During replication, mutations in the form of copying errors and/or chromosomal translocations can occur, causing abnormal cells to form. These abnormal cells can go on to become cancerous. The stimulation of proliferation (mitogenesis) that estrogen causes, increases the chances that abnormal cells will grow into malignant tumors. Estrogen is so potent that it is measured in parts per trillion.

If a woman starts her menstrual cycles early, say, age nine and continues to menstruate into her late 50's, she is at higher risk for breast cancer, as she has been exposed to monthly estrogen elevations for a long period of time. This too is the science behind a recent, well-publicized study that shows that estrogen-based hormone replacement therapy increases the risk of breast cancer.3 In a similar way, birth control pills can elevate breast cancer risk.

2. The earlier a woman's breast matures from prepubescent (Type 1) and pubescent (Type 2) lobules to reproductive (Type 3) and lactation (Type 4) lobules (see diagrams), the lower her risk of breast cancer.4 Type 1 and 2 lobules are known to be where cancers arise, in the TDLUs (terminal ductal lobular units),5 whereas Type 3 and 4 lobules are mature and resistant to carcinogens. When a female child is born, she has only a small number of primitive Type 1 lobules. At puberty, when estrogen levels rise, the breast forms Type 2 lobules. It is only through the hormonal environment and length of a full term (or to at least 32 weeks) pregnancy that there is full maturation of Type 3 and 4 lobules in the breast. This maturation protects a woman and lowers her risk of breast cancer.

This is why women who undergo full term pregnancies have lower risk of breast cancer and why women who remain childless have higher risk of breast cancer. Women who give birth after age 30 are also at increased risk of breast cancer as their immature Type 1 and 2 lobules are exposed to estrogen for the many years between the time of their first menstruation until their first full term pregnancy. Abortion in women under 18 and over 30 years old carries the greatest risk: these women have the highest percentage of Type 1 lobules in their breasts.

It is the interplay of these two principles, estrogen exposure and breast lobule maturation, which accounts for the fact that abortion can lead to breast cancer. Within a few days of conception, a woman's estrogen level rises. By the end of the first trimester, estrogen levels have increased by 2000%. The estrogen stimulation that causes the multiplication of Type 1 and 2 lobules, results in sore and tender breasts early on in pregnancy. It is only after 32 weeks that a woman's breasts stop growing larger and mature into Type 3 and 4 lobules in preparation for breast-feeding.


If abortion ends a woman's pregnancy before full maturation of her breasts, she is left with an increased number of the immature Type 1 and 2 lobules. She now has a greater number of the breast lobules where cancers can arise. This causes her to be at greater risk for breast cancer. It is through this same biologic mechanism that any premature birth before 32 weeks more than doubles breast cancer risk.


Induced abortion thus increases breast cancer risk by two mechanisms. First, abortion leaves the breast with increased numbers of Type 1 and Type 2 lobules, those lobules in which cancer cells are formed, which are then exposed to more estrogen through menstrual cycles. These lobules would otherwise have been protected from cancer by maturation to Type 3 and 4 lobules, if pregnancy had gone to term. Second, the breast is exposed to high levels of estrogen during pregnancy, which can induce cancer cells to form. 6

Types of Breast Lobules

Diagrams taken from Schwartz, Shires, Spencer, eds., Principles of Surgery 5th Ed. (McGraw Hill, 1989)
Breast Cancer Prevention Institute
1. Henderson BE, Ross R, Bernstein L. Estrogen is a cause of human cancer: The Richard and Hilda Rosenthal Foundation Award Lecture. Cancer Research 1988;48:246-53.
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2. Miller, Katherine. Estrogen and DNA damage: The silent source of breast cancer? J Natl Cancer Inst 2003: 95:100-102.
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3. Writing group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women. JAMA 2002;288:321-33.
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4. Diagrams taken from eds. Schwartz, Shires, Spencer, Principles of Surgery (McGraw Hill) Russo J, Tay LK, Russo IH. Differentiation of the mammary gland and susceptibility to carcinogenesis. Breast Cancer Res & Treatment 1982;2:5-73.
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5. Daling JR, Malone DE, Voigt LF, White E, Weiss NS. Risk of breast cancer among young women: relationship to induced abortion. J Natl Cancer Inst 1994;86:1584-92.
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6. Melbye M, et al. Preterm delivery and risk of breast cancer. Brit J Cancer 1999;80:609. Pregnancies that result in first trimester spontaneous abortions produce subnormal estrogen concentrations and generally do not increase breast cancer risk. That is, there is little estrogen stimulation of the breast. Stewart DR, Overstreet JW, Nakajima ST, Lasley BL. Enhanced ovarian steroid secretion before implantation in early human pregnancy. J Clin Endocrinol Metab 1993;76:1470-6. Kunz J, Keller PJ. HCG, HPL, oestradiol, progesterone and AFP in serum in patients with threatened abortion. Br J Obstet Gynaecol 1976;83:640-4. Witt BR, Wolf GC, Wainwright CJ, Johnston PD, Thorneycroft IH. Relaxin, CA-125, progesterone, estradiol, Schwangerschaft protein, and human chorionic gonadotropin as predictors of outcome in threatened and non-threatened pregnancies. Fertil Steril 1990;53:1029-36. Norman RJ, McLoughlin JW, Borthwick GM, Yohkaichiya T, Matthews CD, MacLennan AH, de Kretser DM. Inhibin and relaxin concentrations in early singleton, multiple, and failing pregnancy: relationship to gonadotropin and steroid profiles. Fertil Steril 1993;59:130-7
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Breast Cancer Prevention Institute
Breast Cancer Prevention Institute

Breast Cancer Risks

National Cancer Institute website
An online National Cancer Institute fact sheet was changed to suggest a link between breast cancer and abortions, a move the New York Times called "an egregious distortion" of scientific evidence.

Claiming that abortion can cause breast cancer, social conservatives have pushed for laws across the country that require doctors to provide “counseling” about this alleged risk to all women seeking abortions.[1] As these efforts advanced last year, the Bush Administration distorted the science on this issue to misleadingly portray abortion as a risk factor in breast cancer when there is a scientific consensus that it is not.

Until the summer of 2002, the National Cancer Institute posted an analysis on its web site concluding that the current body of scientific evidence does not support the claim that abortions increase a woman’s risk of breast cancer.[2] The analysis explained that after some uncertainty before the mid-1990s, this issue had been resolved by several well-designed studies, the largest of which was published in the New England Journal of Medicine in 1997,[3] finding no link between abortion and breast cancer risk.

In November 2002, however, the Bush Administration removed this analysis and posted new information about abortion and breast cancer on the NCI web site. The new fact sheet stated:

[T]he possible relationship between abortion and breast cancer has been examined in over thirty published studies since 1957. Some studies have reported statistically significant evidence of an increased risk of breast cancer in women who have had abortions, while others have merely suggested an increased risk. Other studies have found no increase in risk among women who have had an interrupted pregnancy. [4]

This new fact sheet erroneously suggested that whether abortion caused breast cancer was an open question with studies of equal weight supporting both sides. The New York Times called the NCI’s new statement “an egregious distortion of the evidence.”[5] According to the director of epidemiology research for the American Cancer Society, “This issue has been resolved scientifically . . . . This is essentially a political debate.”[6]

After members of Congress protested the change,[7] NCI convened a three-day conference of experts on abortion and breast cancer. Participants reviewed all existing population-based, clinical, and animal data available, and concluded that “[i]nduced abortion is not associated with an increase in breast cancer risk,” ranking this conclusion as “well-established.”[8] On March 21, 2003, the NCI web site was updated to reflect this conclusion.[9]

[1] Texas OKs Disputed Abortion Legislation, Los Angeles Times, 1 (May 22, 2003).

[2] National Cancer Institute, Abortion and Breast Cancer (Mar. 6, 2002).

[3] M. Melbye et al., Induced Abortion and the Risk of Breast Cancer, New England Journal of Medicine, 81–85 (Jan. 9, 1997).

[4] National Cancer Institute, Early Reproductive Events and Breast Cancer (Nov. 25, 2002).

[5] Abortion and Breast Cancer, New York Times (Jan. 6, 2003).

[6] Abortion Foes Seize on Reports of Cancer Link in Ad Campaign, Los Angeles Times (Mar. 24, 2002).

[7] Letter from Rep. Henry A. Waxman et al. to Secretary of Health and Human Services Tommy G. Thompson (Dec. 18, 2002).

[8] National Cancer Institute, Summary Report: Early Reproductive Events and Breast Cancer (Mar. 4, 2003) (online at http://www.cancer.gov/
cancerinfo/ere-workshop-report).

[9] National Cancer Institute, Abortion, Miscarriage, and Breast Cancer Risk (Mar. 21, 2003) (online at http://cis.nci.nih.gov/fact/3_75.htm).

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